miRNet

APIs

Mapping miRNAs to target genes

The following API can be used to get experimentally validated table results of the miRNA-target interactions (forward mapping):

POST table/mir

http://api.mirnet.ca/table/mir

Headers

Content-Type application/json

Body raw (application/json)

  {
    "org": "hsa",
    "idOpt": "mir_id",
    "selSource": "Kidney",
    "targetOpt": "gene",
    "myList": "hsa-mir-101-3p;hsa-mir-133b;hsa-mir-147a;hsa-mir-3140-3p;hsa-mir-361-5p;hsa-mir-510-5p"
  }

    The different options for input parameters are given below:
        <org> = hsa | mmu | rno | bta | ssc | gga | dre | cel | dme | sma
        hsa - H. sapiens (human)
        mmu - M. musculus (mouse)
        rno - R. norvegicus (rat)
        bta - B. taurus (cattle)
        ssc - S. scrofa (pig)
        gga - G. gallus (chicken)
        dre - D. rerio (zebrafish)
        cel - C. elegans (roundworm)
        dme - D. melanogaster (fruitfly)
        sma - S. mansoni (blood fluke)

        <idOpt> = mir_id | mir_acc
        mir_id - miRBase ID
        mir_acc - miRBase Accession

        <selSource> = Exosomes | Bone marrow | Kidney | Pancreas | Cervix | Mammary gland | Brain | Liver | Placenta |
        Embryo | Bone | Intestine | Lung | Breast cancerous tissues | Umbilical vein | Peripheral blood | Skin | 
        Prostate | Gastric | Testis | Muscle | Stomach | Head/neck | Bronchus | Nervous | Others

        <targetOpt> = gene

A list of examples for calling /table/mir using several programming languages is shown below:

R request using httr
require("httr") #install.packages("httr")
require("jsonlite") #install.packages("jsonlite")

base <- "http://api.mirnet.ca"
endpoint <- "/table/mir"
call <- paste(base, endpoint, sep="")
query_input <- "hsa-mir-101-3p;hsa-mir-133b;hsa-mir-147a;hsa-mir-3140-3p;hsa-mir-361-5p;hsa-mir-510-5p"
query_results <- POST(call, 
                      body = list(org = "hsa", 
                                  idOpt = "mir_id", 
                                  selSource = "Kidney", 
                                  targetOpt = "gene",
                                  myList = query_input), encode = "json")

query_results_text <- content(query_results, "text")
query_results_json <- fromJSON(query_results_text, flatten = TRUE)
query_results_df <- as.data.frame(query_results_json)

JavaScript Jquery AJAX 
var settings = {
  "url": "http://api.mirnet.ca/table/mir",
  "method": "POST",
  "timeout": 0,
  "headers": {
    "Content-Type": "application/json"
  },
  "data": JSON.stringify({"org":"hsa","idOpt":"mir_id","selSource":"Kidney","targetOpt":"gene","myList":"hsa-mir-101-3p;hsa-mir-133b;hsa-mir-147a;hsa-mir-3140-3p;hsa-mir-361-5p;hsa-mir-510-5p"}),
};

$.ajax(settings).done(function (response) {
  console.log(response);
});

cURL (command line)  
curl --location --request POST 'http://api.mirnet.ca/table/mir' \
--header 'Content-Type: application/json' \
--data-raw '{
	"org": "hsa",
	"idOpt": "mir_id",
	"selSource": "Kidney",
    "targetOpt": "gene",
	"myList": "hsa-mir-101-3p;hsa-mir-133b;hsa-mir-147a;hsa-mir-3140-3p;hsa-mir-361-5p;hsa-mir-510-5p"
}'

Java Unirest
HttpResponse<String> response = Unirest.post("http://api.mirnet.ca/table/mir")
  .header("Content-Type", "application/json")
  .body("{\n\t\"org\": \"hsa\",\n\t\"idOpt\": \"mir_id\",\n\t\"selSource\": \"Kidney\",\n\"targetOpt\": \"gene\",\n\t\"myList\": \"hsa-mir-101-3p;hsa-mir-133b;hsa-mir-147a;hsa-mir-3140-3p;hsa-mir-361-5p;hsa-mir-510-5p\"\n}\n")
  .asString();
  
Python Requests
import requests
url = "http://api.mirnet.ca/table/mir"
payload = "{\n\t\"org\": \"hsa\",\n\t\"idOpt\": \"mir_id\",\n\t\"selSource\": \"Kidney\",\n\"targetOpt\": \"gene\",\n\t\"myList\": \"hsa-mir-101-3p;hsa-mir-133b;hsa-mir-147a;hsa-mir-3140-3p;hsa-mir-361-5p;hsa-mir-510-5p\"\n}\n"
headers = {
  'Content-Type': 'application/json'
}
response = requests.request("POST", url, headers=headers, data = payload)
print(response.text.encode('utf8'))

Mapping genes to miRNAs

The following API can be used to get experimentally validated table results of the miRNA-target interactions (reverse mapping):

POST table/gene

http://api.mirnet.ca/table/gene

Headers

Content-Type application/json

Body raw (application/json)

  {
    "org": "hsa",
    "idOpt": "symbol",
    "selSource": "Bone marrow",
    "myList": "ACAT1;DDX3X;MEGF9;FMR1;HAPLN1;IL12A;OLR1;RNF6;SOD3;ELOVL4;MRAP2"
  }

    The different options for input parameters are given below:
        <org> = hsa | mmu | rno | bta | ssc | gga | dre | cel | dme | sma
        hsa - H. sapiens (human)
        mmu - M. musculus (mouse)
        rno - R. norvegicus (rat)
        bta - B. taurus (cattle)
        ssc - S. scrofa (pig)
        gga - G. gallus (chicken)
        dre - D. rerio (zebrafish)
        cel - C. elegans (roundworm)
        dme - D. melanogaster (fruitfly)
        sma - S. mansoni (blood fluke)

        <idOpt> = symbol | entrez | embl
        symbol - Official gene symbo
        entrez - Entrez gene ID
        embl - Ensembl gene ID

        <selSource> = Exosomes | Bone marrow | Kidney | Pancreas | Cervix | Mammary gland | Brain | Liver | Placenta |
        Embryo | Bone | Intestine | Lung | Breast cancerous tissues | Umbilical vein | Peripheral blood | Skin | 
        Prostate | Gastric | Testis | Muscle | Stomach | Head/neck | Bronchus | Nervous | Others

A list of examples for calling /table/gene using several programming languages is shown below:

R request using httr
require("httr") #install.packages("httr")
require("jsonlite") #install.packages("jsonlite")

base <- "http://api.mirnet.ca"
endpoint <- "/table/gene"
call <- paste(base, endpoint, sep="")
query_input <- "ACAT1;DDX3X;MEGF9;FMR1;HAPLN1;IL12A;OLR1;RNF6;SOD3;ELOVL4;MRAP2"
query_results <- POST(call, 
                      body = list(org = "hsa", 
                                  idOpt = "symbol", 
                                  selSource = "Bone marrow", 
                                  myList = query_input), encode = "json")

query_results_text <- content(query_results, "text")
query_results_json <- fromJSON(query_results_text, flatten = TRUE)
query_results_df <- as.data.frame(query_results_json)

JavaScript Jquery AJAX 
var settings = {
  "url": "http://api.mirnet.ca/table/gene",
  "method": "POST",
  "timeout": 0,
  "headers": {
    "Content-Type": "application/json"
  },
  "data": JSON.stringify({"org":"hsa","idOpt":"symbol","selSource":"Bone marrow","myList":"ACAT1;DDX3X;MEGF9;FMR1;HAPLN1;IL12A;OLR1;RNF6;SOD3;ELOVL4;MRAP2"}),
};

$.ajax(settings).done(function (response) {
  console.log(response);
});

cURL (command line)  
curl --location --request POST 'http://api.mirnet.ca/table/gene' \
--header 'Content-Type: application/json' \
--data-raw '{
	"org": "hsa",
	"idOpt": "symbol",
	"selSource": "Bone marrow",
	"myList": "ACAT1;DDX3X;MEGF9;FMR1;HAPLN1;IL12A;OLR1;RNF6;SOD3;ELOVL4;MRAP2"
}'

Java Unirest
HttpResponse<String> response = Unirest.post("http://api.mirnet.ca/table/gene")
  .header("Content-Type", "application/json")
  .body("{\n\t\"org\": \"hsa\",\n\t\"idOpt\": \"symbol\",\n\t\"selSource\": \"Bone marrow\",\n\t\"myList\": \"ACAT1;DDX3X;MEGF9;FMR1;HAPLN1;IL12A;OLR1;RNF6;SOD3;ELOVL4;MRAP2\"\n}\n")
  .asString();

Python Requests
import requests
url = "http://api.mirnet.ca/table/gene"
payload = "{\n\t\"org\": \"hsa\",\n\t\"idOpt\": \"symbol\",\n\t\"selSource\": \"Bone marrow\",\n\t\"myList\": \"ACAT1;DDX3X;MEGF9;FMR1;HAPLN1;IL12A;OLR1;RNF6;SOD3;ELOVL4;MRAP2\"\n}\n"
headers = {
  'Content-Type': 'application/json'
}
response = requests.request("POST", url, headers=headers, data = payload)
print(response.text.encode('utf8'))

Generating interaction network for input miRNAs

The following API can be used to get graph data of miRNA-target interactions (json):

POST graph/mir

http://api.mirnet.ca/graph/mir

Headers

Content-Type application/json

Body raw (application/json)

    The different options for input parameters are given below:
        <org> = hsa | mmu | rno | bta | ssc | gga | dre | cel | dme | sma
        hsa - H. sapiens (human)
        mmu - M. musculus (mouse)
        rno - R. norvegicus (rat)
        bta - B. taurus (cattle)
        ssc - S. scrofa (pig)
        gga - G. gallus (chicken)
        dre - D. rerio (zebrafish)
        cel - C. elegans (roundworm)
        dme - D. melanogaster (fruitfly)
        sma - S. mansoni (blood fluke)

        <idOpt> = mir_id | mir_acc
        mir_id - miRBase ID
        mir_acc - miRBase Accession

        <selSource> = Exosomes | Bone marrow | Kidney | Pancreas | Cervix | Mammary gland | Brain | Liver | Placenta |
        Embryo | Bone | Intestine | Lung | Breast cancerous tissues | Umbilical vein | Peripheral blood | Skin | 
        Prostate | Gastric | Testis | Muscle | Stomach | Head/neck | Bronchus | Nervous | Others

        <targetOpt> = gene

A list of examples for calling /graph/mir using several programming languages is shown below:

R request using httr
require("httr") #install.packages("httr")
require("jsonlite") #install.packages("jsonlite")

base <- "http://api.mirnet.ca"
endpoint <- "/graph/mir"
call <- paste(base, endpoint, sep="")
query_input <- "hsa-mir-101-3p;hsa-mir-133b;hsa-mir-147a;hsa-mir-3140-3p;hsa-mir-361-5p;hsa-mir-510-5p"
query_results <- POST(call, 
                      body = list(org = "hsa", 
                                  idOpt = "mir_id", 
                                  selSource = "Kidney", 
                                  targetOpt = "gene",
                                  myList = query_input), encode = "json")

query_results_text <- content(query_results, "text")
query_results_json <- fromJSON(query_results_text, flatten = TRUE)
sink("query_results.json")
cat(query_results_json)
sink()

JavaScript Jquery AJAX 
var settings = {
  "url": "http://api.mirnet.ca/graph/mir",
  "method": "POST",
  "timeout": 0,
  "headers": {
    "Content-Type": "application/json"
  },
  "data": JSON.stringify({"org":"hsa","idOpt":"mir_id","selSource":"Kidney","targetOpt":"gene","myList":"hsa-mir-101-3p;hsa-mir-133b;hsa-mir-147a;hsa-mir-3140-3p;hsa-mir-361-5p;hsa-mir-510-5p"}),
};

$.ajax(settings).done(function (response) {
  console.log(response);
});

cURL (command line)  
curl --location --request POST 'http://api.mirnet.ca/graph/mir' \
--header 'Content-Type: application/json' \
--data-raw '{
	"org": "hsa",
	"idOpt": "mir_id",
	"selSource": "Kidney",
    "targetOpt": "gene",
	"myList": "hsa-mir-101-3p;hsa-mir-133b;hsa-mir-147a;hsa-mir-3140-3p;hsa-mir-361-5p;hsa-mir-510-5p"
}'

Java Unirest
HttpResponse<String> response = Unirest.post("http://api.mirnet.ca/graph/mir")
  .header("Content-Type", "application/json")
  .body("{\n\t\"org\": \"hsa\",\n\t\"idOpt\": \"mir_id\",\n\t\"selSource\": \"Kidney\",\n\"targetOpt\": \"gene\",\n\t\"myList\": \"hsa-mir-101-3p;hsa-mir-133b;hsa-mir-147a;hsa-mir-3140-3p;hsa-mir-361-5p;hsa-mir-510-5p\"\n}\n")
  .asString();
  
Python Requests
import requests
url = "http://api.mirnet.ca/graph/mir"
payload = "{\n\t\"org\": \"hsa\",\n\t\"idOpt\": \"mir_id\",\n\t\"selSource\": \"Kidney\",\n\"targetOpt\": \"gene\",\n\t\"myList\": \"hsa-mir-101-3p;hsa-mir-133b;hsa-mir-147a;hsa-mir-3140-3p;hsa-mir-361-5p;hsa-mir-510-5p\"\n}\n"
headers = {
  'Content-Type': 'application/json'
}
response = requests.request("POST", url, headers=headers, data = payload)
print(response.text.encode('utf8'))

Generating interaction network for input genes

The following API can be used to get graph data of miRNA-target interactions given a gene list input (json):

POST graph/gene

http://api.mirnet.ca/graph/gene

Headers

Content-Type application/json

Body raw (application/json)

  {
    "org": "hsa",
    "idOpt": "symbol",
    "selSource": "Bone marrow",
    "myList": "ACAT1;DDX3X;MEGF9;FMR1;HAPLN1;IL12A;OLR1;RNF6;SOD3;ELOVL4;MRAP2"
  }

    The different options for input parameters are given below:
        <org> = hsa | mmu | rno | bta | ssc | gga | dre | cel | dme | sma
        hsa - H. sapiens (human)
        mmu - M. musculus (mouse)
        rno - R. norvegicus (rat)
        bta - B. taurus (cattle)
        ssc - S. scrofa (pig)
        gga - G. gallus (chicken)
        dre - D. rerio (zebrafish)
        cel - C. elegans (roundworm)
        dme - D. melanogaster (fruitfly)
        sma - S. mansoni (blood fluke)

        <idOpt> = symbol | entrez | embl
        symbol - Official gene symbo
        entrez - Entrez gene ID
        embl - Ensembl gene ID

        <selSource> = Exosomes | Bone marrow | Kidney | Pancreas | Cervix | Mammary gland | Brain | Liver | Placenta |
        Embryo | Bone | Intestine | Lung | Breast cancerous tissues | Umbilical vein | Peripheral blood | Skin | 
        Prostate | Gastric | Testis | Muscle | Stomach | Head/neck | Bronchus | Nervous | Others

A list of examples for calling /graph/gene using several programming languages is shown below:

R request using httr
require("httr") #install.packages("httr")
require("jsonlite") #install.packages("jsonlite")

base <- "http://api.mirnet.ca"
endpoint <- "/graph/gene"
call <- paste(base, endpoint, sep="")
query_input <- "ACAT1;DDX3X;MEGF9;FMR1;HAPLN1;IL12A;OLR1;RNF6;SOD3;ELOVL4;MRAP2"
query_results <- POST(call, 
                      body = list(org = "hsa", 
                                  idOpt = "symbol", 
                                  selSource = "Bone marrow", 
                                  myList = query_input), encode = "json")

query_results_text <- content(query_results, "text")
query_results_json <- fromJSON(query_results_text, flatten = TRUE)
sink("query_results.json")
cat(query_results_json)
sink()

JavaScript Jquery AJAX 
var settings = {
  "url": "http://api.mirnet.ca/graph/gene",
  "method": "POST",
  "timeout": 0,
  "headers": {
    "Content-Type": "application/json"
  },
  "data": JSON.stringify({"org":"hsa","idOpt":"symbol","selSource":"Bone marrow","myList":"ACAT1;DDX3X;MEGF9;FMR1;HAPLN1;IL12A;OLR1;RNF6;SOD3;ELOVL4;MRAP2"}),
};

$.ajax(settings).done(function (response) {
  console.log(response);
});

cURL (command line)  
curl --location --request POST 'http://api.mirnet.ca/graph/gene' \
--header 'Content-Type: application/json' \
--data-raw '{
	"org": "hsa",
	"idOpt": "symbol",
	"selSource": "Bone marrow",
	"myList": "ACAT1;DDX3X;MEGF9;FMR1;HAPLN1;IL12A;OLR1;RNF6;SOD3;ELOVL4;MRAP2"
}'

Java Unirest
HttpResponse<String> response = Unirest.post("http://api.mirnet.ca/graph/gene")
  .header("Content-Type", "application/json")
  .body("{\n\t\"org\": \"hsa\",\n\t\"idOpt\": \"symbol\",\n\t\"selSource\": \"Bone marrow\",\n\t\"myList\": \"ACAT1;DDX3X;MEGF9;FMR1;HAPLN1;IL12A;OLR1;RNF6;SOD3;ELOVL4;MRAP2\"\n}\n")
  .asString();

Python Requests
import requests
url = "http://api.mirnet.ca/graph/gene"
payload = "{\n\t\"org\": \"hsa\",\n\t\"idOpt\": \"symbol\",\n\t\"selSource\": \"Bone marrow\",\n\t\"myList\": \"ACAT1;DDX3X;MEGF9;FMR1;HAPLN1;IL12A;OLR1;RNF6;SOD3;ELOVL4;MRAP2\"\n}\n"
headers = {
  'Content-Type': 'application/json'
}
response = requests.request("POST", url, headers=headers, data = payload)
print(response.text.encode('utf8'))

Enriching a list of miRNAs

The following API can be used to get functional enrichment results for miRNA-target interactions:

POST function/mir

http://api.mirnet.ca/function/mir

Headers

Content-Type application/json

Body raw (application/json)

    The different options for input parameters are given below:
        <org> = hsa | mmu | rno | bta | ssc | gga | dre | cel | dme | sma
        hsa - H. sapiens (human)
        mmu - M. musculus (mouse)
        rno - R. norvegicus (rat)
        bta - B. taurus (cattle)
        ssc - S. scrofa (pig)
        gga - G. gallus (chicken)
        dre - D. rerio (zebrafish)
        cel - C. elegans (roundworm)
        dme - D. melanogaster (fruitfly)
        sma - S. mansoni (blood fluke)

        <idOpt> = mir_id | mir_acc
        mir_id - miRBase ID
        mir_acc - miRBase Accession

        <selSource> = Exosomes | Bone marrow | Kidney | Pancreas | Cervix | Mammary gland | Brain | Liver | Placenta |
        Embryo | Bone | Intestine | Lung | Breast cancerous tissues | Umbilical vein | Peripheral blood | Skin | 
        Prostate | Gastric | Testis | Muscle | Stomach | Head/neck | Bronchus | Nervous | Others

        <targetOpt> = gene

        <algorithm> = hyp
        hyp -- Hypergeometric test

        <dbType> = mirfamily | tissue | func | hmdd | Cluster | tf
        mirfamily - miRNA Family
        tissue - miRNA Tissue
        func - miRNA Function
        hmdd - miRNA Disease
        cluster - miRNA Cluster
        tf - miRNA TF

A list of examples for calling /function/mir using several programming languages is shown below:

R request using httr
require("httr") #install.packages("httr")
require("jsonlite") #install.packages("jsonlite")

base <- "http://api.mirnet.ca"
endpoint <- "/function/mir"
call <- paste(base, endpoint, sep="")
query_input <- "hsa-mir-101-3p;hsa-mir-133b;hsa-mir-147a;hsa-mir-3140-3p;hsa-mir-361-5p;hsa-mir-510-5p"
query_results <- POST(call, 
                      body = list(org = "hsa", 
                                  idOpt = "mir_id", 
                                  selSource = "Kidney", 
                                  targetOpt = "gene",
                                  algorithm = "hyp",
                                  dbType = "mirfamily",
                                  myList = query_input), encode = "json")

query_results_text <- content(query_results, "text")
query_results_json <- fromJSON(query_results_text, flatten = TRUE)
sink("query_results.json")
cat(query_results_json)
sink()

JavaScript Jquery AJAX 
var settings = {
  "url": "http://api.mirnet.ca/function/mir",
  "method": "POST",
  "timeout": 0,
  "headers": {
    "Content-Type": "application/json"
  },
  "data": JSON.stringify({"org":"hsa","idOpt":"mir_id","selSource":"Kidney","targetOpt":"gene","myList":"hsa-mir-101-3p;hsa-mir-133b;hsa-mir-147a;hsa-mir-3140-3p;hsa-mir-361-5p;hsa-mir-510-5p","algorithm":"hyp","dbType":"mirfamily"}),
};

$.ajax(settings).done(function (response) {
  console.log(response);
});

cURL (command line)  
curl --location --request POST 'http://api.mirnet.ca/function/mir' \
--header 'Content-Type: application/json' \
--data-raw '{
	"org": "hsa",
	"idOpt": "mir_id",
	"selSource": "Kidney",
    "targetOpt": "gene",
	"myList": "hsa-mir-101-3p;hsa-mir-133b;hsa-mir-147a;hsa-mir-3140-3p;hsa-mir-361-5p;hsa-mir-510-5p",
	"algorithm": "hyp",
	"dbType": "mirfamily"
}'

Java Unirest
HttpResponse<String> response = Unirest.post("http://api.mirnet.ca/function/mir")
  .header("Content-Type", "application/json")
  .body("{\n\t\"org\": \"hsa\",\n\t\"idOpt\": \"mir_id\",\n\t\"selSource\": \"Kidney\",\n\"targetOpt\": \"gene\",\n\t\"myList\": \"hsa-mir-101-3p;hsa-mir-133b;hsa-mir-147a;hsa-mir-3140-3p;hsa-mir-361-5p;hsa-mir-510-5p\",\n\t\"algorithm\": \"hyp\",\n\t\"dbType\": \"mirfamily\"\n}\n")
  .asString();
  
Python Requests
import requests
url = "http://api.mirnet.ca/function/mir"
payload = "{\n\t\"org\": \"hsa\",\n\t\"idOpt\": \"mir_id\",\n\t\"selSource\": \"Kidney\",\n\"targetOpt\": \"gene\",\n\t\"myList\": \"hsa-mir-101-3p;hsa-mir-133b;hsa-mir-147a;hsa-mir-3140-3p;hsa-mir-361-5p;hsa-mir-510-5p\",\n\t\"algorithm\": \"hyp\",\n\t\"dbType\": \"mirfamily\"\n}\n"
headers = {
  'Content-Type': 'application/json'
}
response = requests.request("POST", url, headers=headers, data = payload)
print(response.text.encode('utf8'))

Enriching a list of genes

The following API can be used to get functional enrichment results for gene-miRNA interactions:

POST function/gene

http://api.mirnet.ca/function/gene

Headers

Content-Type application/json

Body raw (application/json)

  {
    "org": "hsa",
    "idOpt": "symbol",
    "selSource": "Bone marrow",
    "myList": "ACAT1;DDX3X;MEGF9;FMR1;HAPLN1;IL12A;OLR1;RNF6;SOD3;ELOVL4;MRAP2",
    "algorithm": "hyp",
    "dbType": "mirfamily"
  }

    The different options for input parameters are given below:
        <org> = hsa | mmu | rno | bta | ssc | gga | dre | cel | dme | sma
        hsa - H. sapiens (human)
        mmu - M. musculus (mouse)
        rno - R. norvegicus (rat)
        bta - B. taurus (cattle)
        ssc - S. scrofa (pig)
        gga - G. gallus (chicken)
        dre - D. rerio (zebrafish)
        cel - C. elegans (roundworm)
        dme - D. melanogaster (fruitfly)
        sma - S. mansoni (blood fluke)

        <idOpt> = symbol | entrez | embl
        symbol - Official gene symbo
        entrez - Entrez gene ID
        embl - Ensembl gene ID

        <selSource> = Exosomes | Bone marrow | Kidney | Pancreas | Cervix | Mammary gland | Brain | Liver | Placenta |
        Embryo | Bone | Intestine | Lung | Breast cancerous tissues | Umbilical vein | Peripheral blood | Skin | 
        Prostate | Gastric | Testis | Muscle | Stomach | Head/neck | Bronchus | Nervous | Others

        <algorithm> = hyp
        hyp -- Hypergeometric test

        <dbType> = kegg | reactome | bp | mf | cc
        kegg - KEGG
        reactome - Reactome
        bp - GO:BP
        mf - GO:mf
        cc - GO:cc

A list of examples for calling /function/gene using several programming languages is shown below:

R request using httr
require("httr") #install.packages("httr")
require("jsonlite") #install.packages("jsonlite")

base <- "http://api.mirnet.ca"
endpoint <- "/function/gene"
call <- paste(base, endpoint, sep="")
query_input <- "ACAT1;DDX3X;MEGF9;FMR1;HAPLN1;IL12A;OLR1;RNF6;SOD3;ELOVL4;MRAP2"
query_results <- POST(call, 
                      body = list(org = "hsa", 
                                  idOpt = "symbol", 
                                  selSource = "Bone marrow",
                                  algorithm = "hyp",
                                  dbType = "mirfamily",
                                  myList = query_input), encode = "json")

query_results_text <- content(query_results, "text")
query_results_json <- fromJSON(query_results_text, flatten = TRUE)
sink("query_results.json")
cat(query_results_json)
sink()

JavaScript Jquery AJAX 
var settings = {
  "url": "api.mirnet.ca/function/gene",
  "method": "POST",
  "timeout": 0,
  "headers": {
    "Content-Type": "application/json"
  },
  "data": JSON.stringify({"org":"hsa","idOpt":"symbol","selSource":"Bone marrow","myList":"ACAT1;DDX3X;MEGF9;FMR1;HAPLN1;IL12A;OLR1;RNF6;SOD3;ELOVL4;MRAP2","algorithm":"hyp","dbType":"bp"}),
};

$.ajax(settings).done(function (response) {
  console.log(response);
});

cURL (command line)  
curl --location --request POST 'api.mirnet.ca/function/gene' \
--header 'Content-Type: application/json' \
--data-raw '{
	"org": "hsa",
	"idOpt": "symbol",
	"selSource": "Bone marrow",
	"myList": "ACAT1;DDX3X;MEGF9;FMR1;HAPLN1;IL12A;OLR1;RNF6;SOD3;ELOVL4;MRAP2",
	"algorithm": "hyp",
	"dbType": "bp"
}'

Java Unirest
HttpResponse<String> response = Unirest.post("api.mirnet.ca/function/gene")
  .header("Content-Type", "application/json")
  .body("{\n\t\"org\": \"hsa\",\n\t\"idOpt\": \"symbol\",\n\t\"selSource\": \"Bone marrow\",\n\t\"myList\": \"ACAT1;DDX3X;MEGF9;FMR1;HAPLN1;IL12A;OLR1;RNF6;SOD3;ELOVL4;MRAP2\",\n\t\"algorithm\": \"hyp\",\n\t\"dbType\": \"bp\"\n}\n")
  .asString();

Python Requests
import requests
url = "api.mirnet.ca/function/gene"
payload = "{\n\t\"org\": \"hsa\",\n\t\"idOpt\": \"symbol\",\n\t\"selSource\": \"Bone marrow\",\n\t\"myList\": \"ACAT1;DDX3X;MEGF9;FMR1;HAPLN1;IL12A;OLR1;RNF6;SOD3;ELOVL4;MRAP2\",\n\t\"algorithm\": \"hyp\",\n\t\"dbType\": \"bp\"\n}\n"
headers = {
  'Content-Type': 'application/json'
}
response = requests.request("POST", url, headers=headers, data = payload)
print(response.text.encode('utf8'))

APIs

Mapping between miRNAs & genes

Network Generation APIs

Functional enrichment APIs

Mapping miRNAs to target genes

Mapping genes to miRNAs

Generating interaction network for input miRNAs

Generating interaction network for input genes

Enriching a list of miRNAs

Enriching a list of genes